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Symptoms
Noticeable bend during erection.
Discomfort or pain associated with erections.
Difficulty achieving or maintaining an erection.
Loss of penile length.
Causes
The exact cause of Peyronie’s disease is unknown, but it is believed to result from injury or trauma to the penis, genetic factors, and certain connective tissue disorders.
Risk Factors
More common in men over 50.
Genetic predisposition to connective tissue disorders.
Conditions like Dupuytren’s contracture.
Injury or repeated bending of the penis.
Investigations
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To identify symptoms and potential causes.
To assess scar tissue and penile blood flow.
Photographs: Taken during erection to document the degree of curvature.
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Management
Oral Medications: Potassium para-aminobenzoate, pentoxifylline.
Intralesional Injections: Verapamil, collagenase clostridium histolyticum to break down scar tissue.
Surgery to straighten the penis by suturing the longer side to match the shorter, scarred side.
Removal of scar tissue and placement of a graft to straighten the penis.
For men with severe curvature and erectile dysfunction, implants can correct curvature and restore erectile function.
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